hrp0092rfc1.1 | Diabetes and Insulin Session 1 | ESPE2019

Low Prevalence of Maternal Microchimerism in Japanese Children with Type 1 Diabetes

Ushijima Kikumi , Kikuchi Nobuyuki , Kikuchi Toru , Kawamura Tomoyuki , Urakami Tatsuhiko , Amemiya Shin , Ogata Tsutomu , Yokota Ichiro , Sugihara Shigetaka , Fukami Maki

Background: Vertical transfer of maternal cells to the fetus via the placenta leads to maternal microchimerism (MMc) in children. Previous studies from USA have shown that the prevalence and degree of MMc was significantly higher in patients with type 1 diabetes (T1D) than in their unaffected siblings and control individuals. To date, however, the frequency of MMc in non-Caucasian T1D patients remains to be examined.Methods</stro...